10 Best Hotels in Grand Center, St. Louis for 2026

The Fox Theatre with ornate architecture and a marquee.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Compare popular hotels in Grand Center

Property	Star rating	Guest rating
Grand Center Inn	3.0 star property	9.4 Exceptional 105 reviews	View
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton	4.0 star property	8.8 Excellent 1,169 reviews	View
White House at Grand Central	3.5 star property	8.4 Very good 167 reviews	View
Drury Plaza Hotel St. Louis at the Arch	3.0 star property	9.6 Exceptional 3,810 reviews	View
Drury Plaza Hotel St. Louis Brentwood	4.0 star property	9.6 Exceptional 1,013 reviews	View

Where to stay in Grand Center

Find the best Grand Center areas and neighborhoods for the activities you enjoy most.

The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Old Courthouse or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

See properties

A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

See properties

A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

See properties

A historic building with a green dome and adjacent modern high-rise buildings.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

See properties

A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

See properties

Top Grand Center Hotel Reviews

Clayton Plaza Hotel & Extended Stay

8/10 Good

"Even though most of the reviews were great, I was still skeptical because I've had a horrible experience at a highly rated hotel. I must say, the people were telling the truth! The staff was super nice, and the rooms were cleaned. I especially like being able to control the shower temperature digitally. The only downside is that the light in the room is super dim, not great for older eyes. Also, some of the furniture in the room could stand a good deep cleaning. I spray everything down like a mad woman, though. The breakfast buffet was good; however, it never changed in the 3 days I was there, and things like the hash browns and oatmeal were cold. The pool was warm, but could stand a cleaning. Overall, I would stay here again because it was within a 15-minute drive from all of my activities, and as I said, the staff was very nice."

Hollywood Casino & Hotel St. Louis

8/10 Good

"Stayed 1 night for a concert. Typical charges for parking and amenities which will be extra. Walking isn't very friendly to amphitheater even though it's in the same area, would take 30 minutes and not a designated walking area for it. Basically you pay parking twice either for a shuttle or driving to park there. No soap, use body wash. A little overpriced IMO. Bed was nice and comfortable. Hotel very clean and not smokey which is nice. No pool and no free breakfast. We ate at the Italian restaurant but I thought was pricey. If you don't mind spending the money and like to gamble it might be worth it for you. If you're like me and value your money, I won't be back unless the prices drop. Find a cheaper just as good hotel and save $75-$100 bucks on a hotel with pool and free breakfast and drive and park there. Just my 2 cents."

Frequently asked questions

What are the best hotels in Grand Center that travellers recommend?

For a highly recommended hotel in Grand Centre, consider the Angad Arts Hotel St. Louis, Tapestry Collection by Hilton.

This 4-star hotel, with an 8.8 rating, is known for its comfortable and beautiful rooms, featuring premium bedding, deep soaking bathtubs, rainfall showerheads, bathrobes, and Egyptian cotton sheets. Guests frequently praise the friendly and wonderful staff, as well as the wonderful on-site food. The hotel also offers evening entertainment. Its location is perfect, with Powell Hall just 0.1 km away, Vaughn Cultural Centre 0.3 km away, and Ellen Clark Sculpture Park also 0.3 km away.

What are the best family hotels in Grand Center?

For families visiting Grand Centre, the Angad Arts Hotel St. Louis, Tapestry Collection by Hilton, is a superb choice.

This 4-star hotel, with an impressive 8.8 rating, offers a range of features that make it ideal for families. Guests often describe the rooms as comfortable and beautiful, with premium bedding, deep soaking bathtubs, and rainfall showerheads for a relaxing stay. Complimentary cribs are available, and some rooms include a kitchen, which can be very convenient for families. The hotel is well-located, with Powell Hall just 0.1 km away and Vaughn Cultural Centre and Ellen Clark Sculpture Park both within 0.3 km. Families also appreciate the friendly and wonderful staff, and the on-site food is frequently praised as wonderful.

What are the top pet-friendly hotels in Grand Center?

For a top pet-friendly hotel in Grand Centre, the Angad Arts Hotel St. Louis, Tapestry Collection by Hilton, is an excellent choice.

This 4-star hotel, with an 8.8 rating, is highly regarded by guests for its comfortable and beautiful rooms. It specifically permits dogs and offers a range of luxurious amenities such as premium bedding, deep soaking bathtubs, rainfall showerheads, bathrobes, and Egyptian cotton sheets. Guests frequently praise the friendly and wonderful staff, as well as the good on-site dining options. The location is perfect, being just 0.1 km from Powell Hall and 0.3 km from both the Vaughn Cultural Centre and the Ellen Clark Sculpture Park.

What are the best hotels in Grand Center near St. Louis Symphony Orchestra?

For hotels in Grand Centre near the St. Louis Symphony Orchestra, the Angad Arts Hotel St. Louis, Tapestry Collection by Hilton is an excellent choice.

This 4-star hotel, with an 8.8 rating, is located just 0.1 kilometres from Powell Hall, home to the St. Louis Symphony Orchestra, making it incredibly convenient for concertgoers. Guests frequently praise the comfortable and beautiful rooms, which feature premium bedding, deep soaking bathtubs, rainfall showerheads, bathrobes, and Egyptian cotton sheets. For added convenience, kitchens are available, and cribs are provided free of charge, making it suitable for families. The hotel also offers evening entertainment, and guests often comment positively on the friendly and wonderful staff, as well as the good food.

Can I cancel my hotel reservation on Expedia?

Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Grand Center hotel for you.

How much is the nightly rate at a Grand Center hotel?

Hotel prices in Grand Center often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

Explore a world of travel with Expedia

St. Louis Vacation Rentals

Things to do in St. Louis

Book Hotels in Grand Center on Expedia.com

Hotels in Grand Center, St. Louis

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Grand Center hotels

1. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

2. Grand Center Inn

3. White House at Grand Central

4. Element by Marriott St. Louis Midtown

5. Pear Tree Inn St. Louis Near Union Station

6. Drury Plaza Hotel St. Louis Union Station

7. The West End

8. Hyatt Regency St. Louis at The Arch

9. Aloft by Marriott St Louis Central West End

10. Courtyard by Marriott St. Louis Downtown West

11. Fairfield Inn & Suites by Marriott St. Louis Downtown

12. DoubleTree by Hilton St. Louis Forest Park

13. Courtyard by Marriott St. Louis Downtown/Convention Center

14. AC Hotel St. Louis Central West End

15. The Royal Sonesta Chase Park Plaza St. Louis

16. Hotel Indigo St Louis - Central West End by IHG

17. Comfort Inn & Suites Saint Louis Lafayette Square

18. Hampton Inn & Suites St. Louis at Forest Park

19. Live by Loews - St.Louis

20. Drury Plaza Hotel St. Louis at the Arch

Compare popular hotels in Grand Center

Where to stay in Grand Center

Downtown St. Louis

Clayton

St. Charles Historic District

Central West End

Creve Coeur

Top Grand Center Hotel Reviews

Clayton Plaza Hotel & Extended Stay

Frequently asked questions

Explore a world of travel with Expedia